How to run Vector NTI Suite on an Intel Mac

Vector NTI is a very indispensable piece of software once you get used to it. It becomes even more a pain when you cannot use because you switched your computing platform. I’ve seen so many posts from fellow switchers in the academic community with cries of help as to how get their favorite molecular biology workbench app to the mac platform. As of now there aren’t too many solutions! Invitrogen does not seem to be interested in developing the app any longer for the macintosh platform, so the only way is to use the windows version which is under active development and coming out with a new version 11 which i’m curious to try. The workaround for running Vector NTI is pretty simple, run windows on the mac! Using a virtual machine software like the two most popular VMware Fusion and Parallels vector NTI cab run on windows simultaneously. This is very much different from the Bootcamp Windows installation which allows you to run only one operating system at a time. With the virtual machine you can run windows or any other supported Operating systmes virtually within the Mac OS. Although applications like Codeweavers Crossover Office allow you to run Windows applications in a simulated windows environment with WINE, this method did not work out for Vector NTI. My guess is the requirement of Database connectivity (ODBC/MS Jet) that seems to be still a problem in the WINE emulation.

Is this virtual machine work around really a practical workflow? Well i was quite doubtful when i started out, but i’ve been using this workflow for almost a year now and have had no problems. In fact now with the capability of Leopard’s Time machine to backup all files on the mac, my virtual machine and together my Vector NTI database is also backed up constantly. Any files that need to be accessed on the mac can be stored on the shared folder that the virtual machine applications provide that are accessible by both operating systems. Hope this post was helpful for some soul searching for a solution to their Vector NTI woes.


6 responses to “How to run Vector NTI Suite on an Intel Mac”

  1. In fact, VectorNTI is currently the best software available for virtual cloning stuff. I tried many times to find something that would run natively on a new mac and would be of equal functionality but i failed. I have to propose a better alternative. Just install VectorNTI using Darwine on a mac. It works great and you don’t have to install awful windows or any other program.

  2. I switched to a Mac during the summer and have been using vector NTI with success. I am unable to use the control key to select sets of non overlapping sequences to file on my computer.
    Everything was great until last Sunday when I downloaded a VM fusion upgrade. I am now unable to open Vector NTI and get aa message that I am missing a component MCN71.DLL and have to reinstall the program to get it functioning. I tried getting help from VMware, but they don’t really help. I will try reinstalling the program over the weekend. I am disappointed with being able to find a contact who would know what might have happened

    1. why you dont use parallel desktop on mac, i have been using VNTI 11 on parallels desktop for years now without any flaw. I even install VNTI 10 on wine in mac.

  3. I’ve had similar problems to Robert. Now that Invitrogen are proposing to charge for Vector NTI, I’m going to bite the bullet and purchase a supported native Macintosh application like MacVector. The trial version seems to be every bit as good as Vector NTI for cloning, and it was only the cost that held me back before. Has anyone had experience in transferring Vector NTI files to a common format that MacVector or LaserGene can read?

    1. why you dont use parallel desktop on mac, i have been using VNTI 11 on parallels desktop for years now without any flaw. I even install VNTI 10 on wine in mac.

  4. Have a look at Geneious. It supports VNTI import and the cloning support is coming along very well.

    I’m a long time Mac user and it annoys me when companies expect us to run Windows to access their software because they are too lazy to do a port.

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